#skincare - the anti-aging agents with scientifically proven efficacy.

Among so many launches in cosmetics and perfumery, lets be direct: which are the most effective anti-aging agents & formulas (with scientifically proven efficacy) released till now? 

1) Retinol 
It is a derivative of vitamin A, with renewing and rejuvenating actions. It also stimulates the production of new collagen. In general, it is well tolerated and usually doesn't cause redness, dryness or irritations. It should be used at night in the forms of creams for the face or eyelids. 

Retinol improves skin texture, mitigating fine wrinkles, increasing the elasticity and reducing pores size. It also unifies skin coloration. Its use is recommended from the age of 35; follow up with a dermatologist is needed.

2) Vitamin C 
Present in citrus fruits like oranges, lemons and cashew, vitamin C (ascorbic acid) is a potent antioxidant, which can efficiently slow the aging process. It also stimulates the formation of collagen and helps protect the skin from the effects of the sun. It rarely causes irritation, but eventually it may occur on sensitive skin. It is found in many cosmetics for the face, neck and eyes area. Can be used during the day, before the sunscreen, and at night. 

It is suitable from the age of 25. And attention: because it is a chemically unstable compound, vitamin C quickly loses its properties when in contact with the light, oxygen and heat. Therefore, the best products are formulated with active and stabilized forms of the vitamin. The bottles, preferably amber, should protect the product against light and air. 

3) Aquaporins 
They are proteins naturally present in the epidermis, essential for the retention and maintenance of the water in the skin. However, the effectiveness of these natural proteins declines over the years and the skin becomes drier and wrinkled. Therefore, its synthetic version in cosmetics will help moisturize the skin. A well hydrated skin is brighter and has smoother texture and luminosity. Its applicability begins at the age of 30. 

4) Hyaluronic acid
It is a molecule naturally present in the skin, forming a kind of "gelatin" among the collagen and elastin fibers, providing firmness and elasticity. Its synthetic form has moisturizing effect and helps retain water in the skin. Their microparticles have the potential to reach the deep layers of the skin. In dermatologic clinics, the injectable form is used to fill wrinkles and creases. 

Its use can be started from the age of 25. There is no contraindication to the use of hyaluronic acid, except for pregnant women and nursing mothers. 

5) Vitamin E 
Present in foods like nuts, dark green vegetables, eggs yolk and beef liver, is an antioxidant capable of regenerating the skin collagen. Known as tocopherol, it works as an adjunct in the action of other antioxidants, enhancing the results. It also has a protective effect against solar radiation. For a better efficacy in anti-aging treatments, vitamin E is always associated with other ingredients. It is indicated for patients from 25 years and there are no contraindications.